Human Genome Sciences shares jump on test results - Washington Business Journal:

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The company said that, after four years, a mid-stage clinical trial of its former LymphoStat-B lupus drug, now called belimumab and branded as helped improve the conditions of 57 percent of systemic lupuserythematosus patients, compared to 46 percent of patients after only one Human Genome Sciences (NASDAQ: HGSI) also saw a significanf decrease in side effectd between the one-year and four-year assessments. The news gave some comfort to investors, who have been skeptical of thelupusd drug’s chances for success.
With tradinvg volumes at nearly six timewsdaily averages, investors drove Humanj Genome Sciences’ stock up by as much as 28 percent sincer Thursday’s opening bell before it settle d at $3.22, a 19 percent bump, by late afternoon. the company will undergo a more rigorous test on Wall Streefnext month, when it expects to release the firs t batch of results from a late-stage clinicalp trial of belimumab. The second batch is slatedc for aNovember release.
Human Genomw Sciences is in the finakl stages of conductingtwo third-phase trials, each with more than 800 One is lasting for 76 weekw and another for 52 weeks, though both will be measuree for their effectiveness at 52 Lupus, which hasn’t seen a new treatment on the markeft in the last five offers some inviting markegt share to the first company to reverse that, but analysts have brushecd off Human Genome Sciences’ chances as beinh unlikely given how difficult of a disease lupusz is to treat. In March, California-based Genentec h Inc.
and Massachusetts-based Biogen Idec racked up one of the most recentr failuresin third-stage clinical trials for a drug to trear lupus nephritis, a kidney inflammation that’s a complicatiohn of systemic lupus erythematosus. Human Genome initial Phase II trial for belimumab was conducted with 449 patientsz in 2005 in a triakthat hadn’t achieved everything it had set out to do, thoughh patients were measured after less than a year in some casess at that time. The compant continued to track patients who volunteered to remain in the midstagwtrials -- 345 patients, or 77 after 52 weeks; 296 patients, or 66 after 76 weeks; and 213 patients, or 47 as of June 1.

Rodent of the Week: Vaccination via skin patch looks promising - Los Angeles Times

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Los Angeles Times

Rodent of the Week: Vaccination via skin patch looks promising Los Angeles Times The recent H1N1 flu pandemic reminded everyone in public health that our methods for quickly and efficiently vaccinating large numbers of people really ... and more »

Human Capital: People on the move, May 26 - Boston Business Journal:

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, a Billerica-based developefr and manufacturer oflighting technologies, appointex Keith Ward president, CEO and member of the company’s boarf of directors. Prior to joining Luminus Devices, Ward was presiden t and chief operating officer of EYE Lighting Internationapl of NorthAmerica . Patrick named MD at Fireman Capitalk Liam Patrick was named managingf director of Fireman Capital Partners in Patrick previously worked for private equity firmRhoned Group. Fischer hired as VP of fielxd operations for NorthAmerica Lexington-based dynaTracew Software Inc. appointed Eric Fischer vice president of fieldf operations forNorth America.
Fischefr previously served as VP of worldwide sale s for AkorriNetworks , OATSystems Inc. and eRoojm Technology . The law firm of K&LL Gates LLP added Mark Duggan as of counse l in itsBoston office. who is a member of the firm’se investment management practice, joina K&L Gates from State Street GlobalAdvisors , wherw he served as deputgy general counsel and senior vice

Charlie Baker quitting Harvard Pilgrim - Minneapolis / St. Paul Business Journal:

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"Leaving the company is not an easy decisionfor me, but thered is no middle ground. I am either the CEO of HarvarcdPilgrim – or I’m building a campaign I cannot do both," Baker said in a statement released Wednesdat morning. In a fairwell e-mail, Baker thanked Harvard Pilgrim's staffers and touted the organization's successes over the "But I also recognize the terrible financial and operational strain that will face state and local government in theyeara ahead. I know both sectors pretty well betterthan most, I would say and I believe I can bring energy and leadership to the tasks that face state government in the years ahead.
” Baker, a is a former state secretary of administration and finance. CFO Brucd Bullen will be interim CEO atHarvard Pilgrim.

Human Capital: People on the move, July 1 - Tampa Bay Business Journal:

http://www.netnodder.com/authors/author-1258.html
Signature Healthcare of Brockton hirede Steve Friot as director of health carefacilitieds management. He previously served as directoe of facilities operationsat . , a design and constructionj firm with local officesin Worcester, appointed Robert Stephens director of business health care. Stephens has more than 20 years of experiencse marketing and selling design andconstructiojn services. Matthew Tepper joined CB Richard ElliwsInvestors , a real estate investment management as an associate directot for the global multi-manager business. Tepper, formerly of , is based in Boston.
Davis, Malm D’Agostine PC , a Boston-based law firm, added Elise Wald as an associate in the trust and estatespractice area. Wald was previously an associatat Posternak, Blankstein and Lund LLP . Rob MacElhiney , vice presiden of in Weymouth, was named to the board of directorws atthe .

Restaurant industry outlook improves - Triangle Business Journal:

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The Association’s Restaurant Performance Index, or RPI, is a monthlty composite index that tracks the health of and outlook forthe U.S. restaurang industry. It stood at 98.6 in April, up by 0.8 percengt from March, its highest level in 11 months. The findinge are in line with bullish data reportede in theMay 25, 2009, issue of Triangld Business Journal that indicated restaurants in Wake County generallt are faring well. The data show that from July 2008 througbhFebruary 2009, Wake County collected nearly $11.
8 million from a 1 percent tax on prepared food and That’s almost a 7 percent increase from the $11 millio collected in the same period in the previousw fiscal year, according to information provideds by the county. Hudson Riehle, seniotr vice president of research and information services for the Nationa lRestaurant Association, says, “The recent growth in the RPI was drivem by the ‘expectations’ which rose above 100 in Aprilo for the first time in 18 months, a levelp which indicates expansion.
” “Although the RPI’s ‘current indicators are still in a period of contraction, the solid improvemengt in the forward-looking indicators suggests that the end of the industry’s downturn may be in sight, says The RPI is based on responses to the association’x Restaurant Industry Tracking Survey, which is fieldef monthly among restaurant operators nationwide on a variety of including sales, traffic, labor and capital The index consists of two componentas — the Current Situation Index and the Expectation Index.
The Current Situation Index, which measured current trends in four industryindicators (same-storre sales, traffic, labor and capital expenditures), stood at 97.0 in up by 0.9 percent from March and its highesty level since August 2008. April represented the 20th consecutive monthbelow 100, which continues to signify contraction in the current situatiob indicators. Restaurant operators reportedx negative customer traffic levelsx for the 20th consecutive monthin April.
Abourt 23 percent of restauranf operators reported an increase in customeer traffic between April 2008 and April up from 20 percent who reported similarlyin Also, 60 percent of operators reportede a traffic decline in April, down from 63 percentr who reported similarly in March. Restaurant operators also continue to grow more optimisticv aboutthe economy, with 37 percent sayinh they expect economic conditions to improve in six up from 30 percent who reported similarly last montyh and the highest level in threre years. In comparison, only 16 percent of operators expect economic conditions to worsen insix months, down from 21 percenyt last month. The Washington, D.C.
-based Nationa l Restaurant Association is a businessd association for therestaurant industry, comprising 945,0000 restaurant and foodservice outlets and a work force of 13 million employees.

Android This Week: Angry Birds; Galaxy Tab - GigaOm (blog)

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TechRadar UK

Android This Week: Angry Birds; Galaxy Tab GigaOm (blog) 4, 2010, 6:00am PDT No Comments The collective groans of supervisors  »